| Name | City | Management type |
|---|---|---|
| Arroyo Grande High | Arroyo Grande | Public |
| Atascadero High | Atascadero | Public |
| Coast Union High | Cambria | Public |
| Grizzly Challenge Charter | San Luis Obispo | Charter |
| Mission College Preparatory | San Luis Obispo | Private |
| Morro Bay High | Morro Bay | Public |
| Nipomo High | Nipomo | Public |
| Paso Robles High | Paso Robles | Public |
| San Luis Obispo High | San Luis Obispo | Public |
| Shandon High | Shandon | Public |
| Templeton High | Templeton | Public |